by Jeffrey Dach MD
Left Image: Courtesy of John Crisler DO at A4M HCG Low Testosterone
HCG stands for Human Chorionic Gonadotropin. HCG is a bio-identical human hormone that has been well known for decades in medical research and clinical medicine as a hormone secreted by the placenta in the pregnant female. In fact, measuring HCG in the female is the basis for the pregnancy test. If HCG goes up, that means a viable pregnancy. If HCG drops, or goes down, that means miscarriage or an aborting fetus.
The male analog of HCG is LH, also called Leuteinizing hormone secreted by the anterior pituitary. HCG is almost identical to LH (leutinizing hormone from the anterior pituitary), and serves as an LH analog in the male.
In the male, LH is a hormone messenger that instructs the testicle to make more testosterone. So injecting HCG, will do the same thing, it stimulates the testicle to make more testosterone, thereby raising blood testosterone levels, and resolving a low testosterone condition.
Younger males have plenty of reserve ability to make testosterone, and testosterone levels will promptly go up after an injection of HCG. In older males, above the age of 50, the aging process reduces the ability of the testicle to make testosterone to a variable degree. Some older males will have a good response to HCG, other will have a small response, with small amounts of testosterone production. That’s why Dr Eugene Shippen devised the HCG Stimulation Test to help determine if HCG would be helpful or not.
We have been using the John Crisler HCG Protocol and have found that it is very useful for most males with low testosterone. Again, thanks goes to John Crisler for sharing his HCG protocol. John is an excellent resource, and a good friend, and we have collaborated on cases and exchanged ideas freely. He is well known as an excellent speaker on the medical lecture circuit, and I can recommend him if you are in need of a physician. His contact information is: John Crisler D.O. All Things Male – Center for Men’s Health, 919 Chester, Main Floor, Lansing, Michigan 48912 Office Phone: 517-485-4424
Links and References
John Crisler D.O. HCG Protocol
HCG Update – John Crisler D.O.
All Things Male – Center for Men’s Health, 919 Chester, Main Floor, Lansing, Michigan 48912 Office Phone: 517-485-4424
An Update To The Crisler HCG Protocol
David Z’s Primer on TRT, HCG and E2 Management – Part 1 of 2
Eugene Shippen MD Primer on HCG
Chapter 4:The Hormone Universe Shippen’s book chapter 4
eugene shippen HCG-Prior to HCG therapy, Eugene Shippen HCG Stimulation test
Low-Dose Human Chorionic Gonadotropin Maintains Intratesticular Testosterone in Normal Men with Testosterone-Induced Gonadotropin Suppression
Andrea D. Coviello, Alvin M. Matsumoto, William J. Bremner, Karen L. Herbst, John K. Amory, Bradley D. Anawalt, Paul R. Sutton, William W. Wright, Terry R. Brown, Xiaohua Yan, Barry R. Zirkin and Jonathan P. Jarow The Journal of Clinical Endocrinology & Metabolism Vol. 90, No. 5 2595-2602
These results demonstrate that relatively low dose hCG maintains ITT within the normal range in healthy men with gonadotropin suppression. Extensions of this study will allow determination of the ITT concentration threshold required to maintain spermatogenesis in man.
Diurnal rhythm of testosterone induced by human chorionic gonadotrophin (hCG) therapy in isolated hypogonadotrophic hypogonadism: a comparison between subcutaneous and intramuscular hCG administration. T Hugh Jones, Joe F Darne and Hugh HG McGarrigle Jones TH, Darne JF, McGarrigle HHG.
Diurnal rhythm of testosterone induced by human chorionic gonadotrophin (hCG) therapy in isolated hypogonadotrophic hypogonadism: a comparison between subcutaneous and intramuscular hCG administration. Eur J Endocrinol 1994;131:173–8. ISSN 0804–4643
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