Above chart:  darker states have greater number of vaccinated children.  Red circle is number of autism cases. (1)

Autism Increases as Vaccination Rate Increases

Removal of the mercury (thimerosol) preservatives from most vaccines has been done, and yet the expected decrease in autism has not materialized.  This has prompted the suggestion that the vaccine itself is the trigger for autism.  A 2011 study by Gayle DeLonga found a positive correlation between number of vaccinated children and numbers of autism:(1)

“The higher the proportion of children receiving recommended vaccinations, the higher was the prevalence of Autism or Language Delay. A 1% increase in vaccination was associated with an additional 680 children having Autism of Language Delay.”(1)

Study the Unvaccinated Children Autism Rates

Gayle Delonga says:“A follow-up study could investigate the prevalence of autism among unvaccinated children. Other children who typically are not vaccinated could be surveyed. These groups include the Amish and children served by Homefirst, a health clinic near Chicago (Eisenstein, 2009), as well as some home-schooled children or younger siblings of children with autism whose parents decided not to vaccinate. Incremental analysis could also determine the increase or decrease of the prevalence of autism or speech disorders as the number or type of vaccinations increased. A study of vaccinated versus unvaccinated children is useful and feasible.”(1)

Linear Correlation Between Hospitalizations and Doses of Vaccines

A study by Goldman in 2012 reviewed the data from the Vaccine Adverse Event Reporting System (VAERS) on hospitalizations and mortality among infants according to number of vaccine doses and age.  He found a linear correlation between number of vaccine doses and hospitalization rates.  He also found a reverse linear correlation between age of vaccination and autism rate, (2) See data charts below:

Goldman-Miller_Study_12-27-11 fig 3

Fig 3. Hospitalization rate (%) versus the number of vaccine doses among infants, Vaccine Adverse Event Reporting System (VAERS), 1990–2010.

Goldman-Miller_Study_12-27-11 fig 4

Fig 4. Hospitalization rate (%) versus age (in 0.1 year increments) among infants receiving 1–8 vaccine doses, Vaccine Adverse Event Reporting System (VAERS), 1990–2010.

Mortality Data

The data showed:  “an increased mortality rate associated with 5–8 vaccines relative to 1–4 vaccines; (d) a decreased mortality rate associated with children aged 0.5 to <1 year relative to those aged <0.5 year; and (e) a 1.4 male-to-female infant mortality ratio.”

Jeffrey Dach MD

This article is part three of a series

For Part One, Click Here

For Part Two, Click Here

Links and References

http://www.ncbi.nlm.nih.gov/pubmed/21623535
http://www.tandfonline.com/doi/full/10.1080/15287394.2011.573736
1)  Journal of Toxicology and Environmental Health, Part A: Current Issues Volume 74, Issue 14, 2011
A Positive Association found between Autism Prevalence and Childhood Vaccination uptake across the U.S. Population
Gayle DeLonga* pages 903-916 Department of Economics and Finance, Baruch College/City University of New York, New York, New York, USA.

The reason for the rapid rise of autism in the United States that began in the 1990s is a mystery. Although individuals probably have a genetic predisposition to develop autism, researchers suspect that one or more environmental triggers are also needed. One of those triggers might be the battery of vaccinations that young children receive. Using regression analysis and controlling for family income and ethnicity, the relationship between the proportion of children who received the recommended vaccines by age 2 years and the prevalence of autism (AUT) or speech or language impairment (SLI) in each U.S. state from 2001 and 2007 was determined. A positive and statistically significant relationship was found: The higher the proportion of children receiving recommended vaccinations, the higher was the prevalence of AUT or SLI.

A 1% increase in vaccination was associated with an additional 680 children having AUT or SLI. Neither parental behavior nor access to care affected the results, since vaccination proportions were not significantly related (statistically) to any other disability or to the number of pediatricians in a U.S. state. The results suggest that although mercury has been removed from many vaccines, other culprits may link vaccines to autism. Further study into the relationship between vaccines and autism is warranted.

The recent explosion in the prevalence of autism suggests the existence of one or more environmental triggers (Blaxill 2004). Could one of those triggers be the battery of vaccinations given to young children?

Future Directions for Research

Comparing the prevalence of autism among children who are fully vaccinated and those who are not vaccinated at all would be enlightening. In their study “Children Who Received No Vaccines: Who Are They and Where Do They Live?” Smith et al. (2004) used data from the U.S. National Immunization Survey to determine the location of unvaccinated children. A follow-up study could investigate the prevalence of autism among unvaccinated children. Other children who typically are not vaccinated could be surveyed. These groups include the Amish and children served by Homefirst, a health clinic near Chicago (Eisenstein, 2009), as well as some home-schooled children or younger siblings of children with autism whose parents decided not to vaccinate. Incremental analysis could also determine the increase or decrease of the prevalence of autism or speech disorders as the number or type of vaccinations increased. A study of vaccinated versus unvaccinated children is useful and feasible.

2) http://www.ncbi.nlm.nih.gov/pubmed/22531966

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3547435/
Hum Exp Toxicol. 2012 Oct;31(10):1012-21.
Relative trends in hospitalizations and mortality among infants by the number of vaccine doses and age, based on the Vaccine Adverse Event Reporting System (VAERS), 1990-2010.  Goldman GS, Miller NZ. Computer Scientist, Pearblossom, CA 93553, USA.

In this study, the Vaccine Adverse Event Reporting System (VAERS) database, 1990-2010, was investigated; cases that specified either hospitalization or death were identified among 38,801 reports of infants. Based on the types of vaccines reported, the actual number of vaccine doses administered, from 1 to 8, was summed for each case. Linear regression analysis of hospitalization rates as a function of (a) the number of reported vaccine doses and (b) patient age yielded a linear relationship with r(2) = 0.91 and r(2) = 0.95, respectively. The hospitalization rate increased linearly from 11.0% (107 of 969) for 2 doses to 23.5% (661 of 2817) for 8 doses and decreased linearly from 20.1% (154 of 765) for children aged <0.1 year to 10.7% (86 of 801) for children aged 0.9 year. The rate ratio (RR) of the mortality rate for 5-8 vaccine doses to 1-4 vaccine doses is 1.5 (95% confidence interval (CI), 1.4-1.7), indicating a statistically significant increase from 3.6% (95% CI, 3.2-3.9%) deaths associated with 1-4 vaccine doses to 5.5% (95% CI, 5.2-5.7%) associated with 5-8 vaccine doses. The male-to-female mortality RR was 1.4 (95% CI, 1.3-1.5). Our findings show a positive correlation between the number of vaccine doses administered and the percentage of hospitalizations and deaths. Since vaccines are given to millions of infants annually, it is imperative that health authorities have scientific data from synergistic toxicity studies on all combinations of vaccines that infants might receive. Finding ways to increase vaccine safety should be the highest priority.

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