Jeffrey Dach MD » Is Your Baby Toxic from Environmental Chemicals ?

Is Your Baby Toxic from Environmental Chemicals ?

Is Your Baby Toxic from Environmental Chemicals?

by Jeffrey Dach MD

There is alarming news from the University of California about toxic chemicals in virtually all pregnant women. Tracey Woodruff found 163 different chemicals in pregnant women including banned Flame Retardants and DDT. A previous 2004 study showed 287 toxic chemicals in babies cord blood samples. How do we avoid it and what can we do about it?

Tracey Woodruff found 163 different toxic chemicals in pregnant women (1-9).
Here is the partial list:

1) polychlorinated biphenyls (PCBs),
2) organochlorine pesticides, (DDT)
3) perfluorinated compounds (PFCs),
4) polybrominated diphenyl ethers (PBDEs),
5) phthalates
6) perchlorates

Banned Chemicals Dangerous to Health – Flame Retardants and DDT

Polybrominated Diphenyl Ethers (PBDEs) are flame retardant chemicals now banned in many states. DDT is a pesticide banned in the United States since 1972. (1-9)

Below image: Pouring pesticides on the farm courtesy of wikimedia commons. This ends up in our bodies.

287 Different Toxic Chemicals in the Baby

A 2004 study showed 287 toxic chemicals in babies cord blood. Ten random samples of newborn umbilical cord blood from the Red Cross showed 287 environmental chemicals. (10-14).

Here is a partial list of 287 toxic chemicals in the baby:

Mercury in all samples at 0.947 (ppb).
PAH – Polyaromatic hydrocarbons (PAHs) 285 parts per trillion (ppt). (gasoline)
PBDB- Polybrominated dibenzodioxins 55.9 ppt. flame retardants
PFC- Perfluorinated chemicals (PFCs) Scotchguard fabric protectants, Teflon.
OC- Organochlorine pesticides (OCs) 18,600 ppt. – DDT, banned in 1972.
PBDE- Polybrominated diphenyl ethers (PBDEs) 6,420 ppt. flame retardant
PCN- Polychlorinated naphthalenes (PCNs) wood preservatives.
PCB- polychlorinated biphenyls (PCBs) banned in 1976

Meet the most Contaminated Animal on the Planet

No Place to Run – Toxic Contamination in the Arctic Circle

You might think polar bears are safe from industrial pollution. You might think there are pristine places on the earth like the Arctic Circle that represent a safe haven from the chemicals. Perhaps we can run away and avoid this toxic chemical soup. Nope, think again. Arctic polar bears are the most contaminated on the planet thanks to a bio-magnification effect as we go higher up in the food chain.(15) The toxic chemicals get more concentrated as we trace it from insect to fish to polar bear fat stores. Toxic chemical laden wildlife are food staples for the native Inuit peoples of the Arctic Circle resulting in high levels of PCB contamination.(16)

Inuit People of the Arctic – Health Effects of Toxic Contamination

Arctic Inuit women consume 14 times the tolerable intake of chlordane, toxaphene, PCBs and other pesticides causing infertility, stillbirths and birth defects. Many of the children have compromised immune systems with increased cases of otitis media that leave them hearing impaired.(17-22)

What’s going on in the Neighborhood – Thyroid Problems

Long term studies of contaminants in human milk were done in Sweden over 30 years finding a recent increase (doubling over 5 years) of banned PBDEs (used as a fire retardant) (23) This chemical contains bromine and is toxic to the thyroid gland.(24-26)

Hormonal Disruption

Volumes of research over decades have now fully documented the hormonal disruption of pesticides in wild-life and humans (27-31) Certain fruits and vegetables are higher in pesticide exposure and are to be avoided, or use organic. (32) Even though the toxic pesticides such as DDT, Lindane, Eldrin etc. have been banned in the US, they continue to be manufactured and exported to developing countries. 108,000 metric tons of banned pesticides were exported from the U.S. to developing countries from 1992 to 1994. (33) Global pesticide use has been increasing about 1% per year in step with population growth, also about 1% per year.(35)

Neurotoxicity

In addition to the thyroid and hormonal disruption, other studies have shown that organochloride pesticides cause neurotoxicity. (36)

The Politics of Pollution – Chemical Industry Lobby vs. The People

President Bush “Rolls Back” and Dismantles Environmental Protection

You might ask why we have such deplorable chemical pollution of the adornment, wildlife and the bodies of our children? Where is the regulatory oversight of the chemical industry? The answer is that regulation was dismantled under the Bush administration in order to placate the demands of the chemical industry for less regulation and more profits. Here is a list of the 100 worse “rollbacks” of environmental protection by the Bush administration.

Killed – The Toxic Substances Control Act – TSCA

In the first half of 2010, the chemical industry spent 40 million on lobbying , effectively killing the toxic chemical reform bill in Congress. “Despite overwhelming public support for stronger laws on toxic chemicals, Congress has heeded the aggressive opposition of chemical industry lobbyists rather than the support of the American electorate and failed to pass TSCA reform legislation three times in the last six years. However, the battle will continue at the federal level in 2011, with new TSCA reform bills expected to be introduced.” Quoted from healthychild.org

If you want to save the environment from toxic chemicals, you have to fight the chemical industry lobbyists. Call your congressman in support of the TSCA bill.

Addendum 3/9/15: The Case for Banning Glyphosate

Will Richmond Reject Monsanto’s Roundup? The Case for Banning Glyphosate February 2015 By Jeff Ritterman, M.D., Truthout.

Glyphosate, the Monsanto’s Round-Up herbicide commonly used on GMO soy called “Round-up Ready Soy” has been implicated in birth defects and spontaneous abortions by upregulating the Vitamin A pathway in embryos. Glyphosate also causes DNA damage, and increases cancer incidence. Glyphosate afects the Shikimate pathway which kills of gut bacteria. Peasant farmers in Central America, Sri Lanka and India exposed to Glyphosate develop chronic toxic kidney disease and kidney failure. See this article: Int. J. Environ. Res. Public Health 2014, 11(2), 2125-2147; Hypothesis Glyphosate, Hard Water and Nephrotoxic Metals: Are They the Culprits Behind the Epidemic of Chronic Kidney Disease of Unknown Etiology in Sri Lanka? Channa Jayasumana , Sarath Gunatilake and Priyantha Senanayake February 2014.

Gylphosate is a heavy metal chelating agent which forms complexes which damage the renal tubules. Both El Salvador and Sri Lanka have banned glyphosate.

This is Part One of a series
Part Two Risk Factors For Breast Cancer Wrong Again
Part Three Great Women in Medicine Rachel Carson

Jeffrey Dach MD
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Links and References

All Images courtesy of wikimedia commons

regnant_woman2.jpg”>http://commons.wikimedia.org/wiki/Fileregnant_woman2.jpg
Photograph of abdomen of a pregnant woman

http://commons.wikimedia.org/wiki/File:Baby_2.jpg
Baby

http://commons.wikimedia.org/wiki/File:Hazardous-pesticide.jpg
Pesticide to be sprayed on food crops.
From USDA http://www.usda.gov/oc/photo/94cs3568.htm

http://commons.wikimedia.org/wiki/File:Eskimo_Family_NGM–v31–p564.jpg
Eskimo Family NGM–v31–p564…National Geographic Magazine, Volume 31 (1917), page 564.

olarb%C3%A4r_12_2004-11-17.jpg”>http://commons.wikimedia.org/wiki/Fileolarb%C3%A4r_12_2004-11-17.jpg
polar bear

Toxins Found in Pregnant Women

(1) http://ehp03.niehs.nih.gov/article/fetchArticle.action?articleURI=info%3Adoi%2F10.1289%2Fehp.1002727

Woodruff TJ, Zota AR, Schwartz JM 2011. Environmental Chemicals in Pregnant Women in the US: NHANES 2003-2004. Environ Health Perspect

(2) http://ehp03.niehs.nih.gov/article/info:doi/10.1289/ehp.1002727
Environmental Chemicals in Pregnant Women in the US: NHANES 2003-2004
Tracey J. Woodruff, Ami R. Zota, Jackie M. Schwartz

Conclusions: Pregnant women in the U.S. are exposed to multiple chemicals. Further efforts are warranted to understand sources of exposure and implications for policy-making.

(3) http://www.eurekalert.org/pub_releases/2011-01/uoc—us011211.php

UCSF study identifies chemicals in pregnant women

The bodies of virtually all U.S. pregnant women carry multiple chemicals, including some banned since the 1970s and others used in common products such as non-stick cookware, processed foods and personal care products, according to a new study from UCSF. The study marks the first time that the number of chemicals to which pregnant women are exposed has been counted.

Analyzing data for 163 chemicals, researchers detected polychlorinated biphenyls (PCBs), organochlorine pesticides, perfluorinated compounds (PFCs), phenols, polybrominated diphenyl ethers (PBDEs), phthalates, polycyclic aromatic hydrocarbons (PAHs) and perchlorate in 99 to 100 percent of pregnant women. Among the chemicals found in the study group were PBDEs, compounds used as flame retardants now banned in many states including California, and dichlorodiphenyltrichloroethane ( DDT), an organochlorine pesticide banned in the United States in 1972.

(4)
As”>www.sfgate.com/cgi-bin/blogs/inthemission/detail?entry_id=80376
As UCSF Study and Others Continue to Show BPA Problems, What’s A Consumer to Do?

(5) http://news.ucsf.edu/releases/ucsf-study-identifies-chemicals-in-pregnant-women/

Bisphenol A (BPA), which makes plastic hard and clear, and is found in epoxy resins that are used to line the inside of metal food and beverage cans, was identified in 96 percent of the women surveyed. Prenatal exposure to BPA has been linked to adverse health outcomes, affecting brain development and increasing susceptibility to cancer later in life, according to the researchers.

(6) http://www.environmentalhealthnews.org/ehs/newscience/widespread-chemical-exposure-in-pregnant-us-women
Banned, contemporary chemicals widespread in U.S. pregnant women. Jan 14, 2011

(7) http://www.medicalnewstoday.com/articles/213776.php
Most US Pregnant Women Have Cocktail Of Chemicals Inside Them

(8) http://www.fairwarning.org/2011/01/researchers-find-long-banned-chemicals-in-pregnant-women/
Researchers Find Long-Banned Chemicals in Pregnant Women By Matthew Heller on January 17, 2011

(9) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2628162/?tool=pubmed
Environ Res. 2008 October; 108(2): 260–267.
Urinary metabolite concentrations of organophosphorous pesticides, bisphenol A, and phthalates among pregnant women in Rotterdam, the Netherlands: The Generation R Study

Chemicals in Cord Blood

(10) http://www.medpagetoday.com/PublicHealthPolicy/EnvironmentalHealth/1371
Toxin Traces Found in Umbilical Cord Blood By Katrina Woznicki,
Published: July 18, 2005 Reviewed by Zalman S. Agus, MD; Emeritus Professor at the University of Pennsylvania School of Medicine .

WASHINGTON, July 18-Traces of pesticides, industrial byproducts, and mercury were found in the umbilical cord blood of all 10 newborns in a small study.

(11) http://www.medpagetoday.com/PublicHealthPolicy/EnvironmentalHealth/1371
Toxin Traces Found in Umbilical Cord Blood

The researchers found a total of 287 chemicals from the entire group including two chemicals that were banned in the 1970s and other chemicals used in gasoline, garbage treatment, power plants, the production of flame-resistant products, plastics, Teflon, and wood preservatives. Some of these chemicals have been linked to cancer, endocrine disruption, and neurological impairment.

(12) http://www.organicconsumers.org/articles/article_19801.cfm
232 Toxic Chemicals Found in Cord-Blood of Minority Babies

(13) http://scienceinthetriangle.org/2010/09/10-americans-industrial-toxins-found-in-umbilical-cord-blood/
10 Americans: Industrial toxins found in umbilical cord blood Wednesday, September 22, 2010, 4:04 pm By Sabine Vollmer

(14) http://scholar.google.com/scholar?q=toxic+chemicals+cord+blood&hl=en&prmd=ivns&wrapid=tlif129518356798510&um=1&ie=UTF-8&sa=N&tab=ws
google scholar search keywords toxic chemicals cord blood

Toxins in Arctic Eskimos Polar Bears

(15) http://www.thestar.com/news/world/article/905374–polar-bears-in-remote-north-have-high-levels-of-toxic-pollutants

(16) http://news.nationalgeographic.com/news/2004/08/0827_040827_tvarctic_toxins.html
Infiltrating the Food Chain

Persistent organic pollutants are industrial chemicals that break down slowly and collect in the fatty tissues of animals. The toxins have been found to accumulate in ever larger concentrations in species higher up the food chain—a process known as bioaccumulation. In 1970 the insecticide DDT was found in the blubber of ringed seals in the Arctic. By the mid-1970s it was also found in beluga whales, polar bears, and fish. Further tests discovered traces of some of the world’s most toxic industrial chemicals, including polychlorinated biphenyls (PCBs) and dioxin, in Arctic wildlife. In 1987 high levels of PCBs were discovered in nursing Inuit mothers in Nunavut, a semiautonomous territory in the Canadian Arctic.

(17) http://coldclearanddeadly.com/

Inuit: POPs enter the food chain at the microscopic level and remain in the fat of living creatures, bioaccumulating up the food chain to the point that the fat of Arctic narwhal and beluga whales would be classified as hazardous waste. Inuit of Northern Canada and Greenland, who consume this fat as well as that of seals, polar bear and walrus as a portion of their diet, are highly contaminated. Canadian Inuit women of child bearing age consume 14 times the tolerable daily intake (TDI) of chlordane, toxaphene, PCBs and other pesticides. They suffer infertility, stillbirths and birth defects. Many of their children have compromised immune systems, suffering near constant colds and flus that leave them hearing impaired.

Autopsy samples of Inuit Natives show high PCB contamination

(18) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1566611/pdf/envhper00515-0089.pdf
http://www.ncbi.nlm.nih.gov/sites/ppmc/articles/PMC1566611/
Environ Health Perspect. 1999 October; 107(10): 823–828. PMCID: PMC1566611
Concentration of organochlorines in human brain, liver, and adipose tissue autopsy samples from Greenland. E Dewailly, G Mulvad, H S Pedersen, P Ayotte, A Demers, J P Weber, and J C Hansen

Comparisons with available international data on adipose tissue levels reveal that the organochlorine body burden in the Inuit population of Greenland is presently among the highest resulting from environmental exposure.

Infections in Inuit-Otitis Media

(19) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1637954/pdf/envhper00304-0061.pdf
Susceptibility to Infections and Immune Status in Inuit Infants Exposed to Organochlorines
Eric Dewailly,12 Pierre Ayotte,1,2 Suzanne Bruneau,1 Suzanne Gingras,1 Marthe Belles-Isles,3 and Raynald Roy3

We investigated whether organochlorine exposure is associated with the incidence of infectious
diseases in Inuit infants from Nunavik (Arctic Quebec, Canada). We conclude that prenatal organochlorine ecposure could be a risk factor for acute otitis media in Inuit infants.

(20) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1519892/pdf/envhper00377-0064.pdf
Inuit Exposure to Organochlorines through the Aquatic Food Chain in Arctic Quebec

(21) http://www.commondreams.org/headlines01/0519-01.htm
Published on Saturday, May 19, 2001 in the Sydney Morning Herald
Native Peoples Pay the Price of a Poisoned Arctic Industrial Pollutants are Entering the Food Chain by DeNeen Brown in Iqaluit, Nunavut

(22) http://www.ienearth.org/docs/pops_arctic.html
Toxic-tainted Arctic animals passing poisons on to Inuit May 2001 By DeNeen L. Brown The Washington Post

Contaminants in Human Milk

(23) http://www.ncbi.nlm.nih.gov/pubmed/10739053
Chemosphere. 2000 May-Jun;40(9-11):1111-23.
Certain organochlorine and organobromine contaminants in Swedish human milk in perspective of past 20-30 years. Norén K, Meironyté D. Department of Medical Biochemistry and Biophysics, Karolinska Institutet, Stockholm, Sweden.

The investigations of organochlorine compounds in breast milk from women living in the Stockholm region started in 1967. The present study summarises the investigations of polychlorinated biphenyls (PCBs), naphthalenes (PCNs), dibenzo-p-dioxins (PCDDs), dibenzofurans (PCDFs), polybrominated diphenyl ethers (PBDEs) and pesticides (DDT, DDE, hexachlorobenzene, dieldrin) as well as methylsulfonyl metabolites of PCBs and DDE in human milk sampled during different periods up to 1997. During the course of 20-30 yr the levels of organochlorine compounds in human milk have decreased to various extent. A decrease to the half of the original concentration was attained in the range of 4-17 yr periods. On the contrary to the organochlorine compounds, the concentrations of PBDEs have increased during the period 1972-1997, indicating a doubling of the levels by 5 yr. The levels reflect the environmental contamination and background levels in the population. The accumulation and ongoing increase in the levels of PBDEs calls for immediate measures to stop the environmental pollution and human exposure to PBDEs.

Flame Retardants and Thyroid

(24) http://www.ncbi.nlm.nih.gov/pubmed/9828307
Chemosphere. 1998 Oct-Nov;37(9-12):1789-93.
Postnatal exposure to chlorinated dioxins and related chemicals on thyroid hormone status in Japanese breast-fed infants. Nagayama J, Okamura K, Iida T, Hirakawa H, Matsueda T, Tsuji H, Hasegawa M, Sato K, Ma HY, Yanagawa T, Igarashi H, Fukushige J, Watanabe T.

Effects of postnatal exposure to polychlorinated dibenzo-p-dioxins (PCDDs), polychlorinated dibenzofurans (PCDFs) and coplanar polychlorinated biphenyls (Co-PCBs) on thyroid hormone status were studied in the peripheral blood of 36 breast-fed Japanese infants. Estimated total intakes of these chemicals in toxic equivalent quantity (TEQ) converted into 2,3,7,8-tetrachlorodibenzo-p-dioxin (2,3,7,8-TCDD) from the breast milk significantly and negatively correlated with the levels of triiodothyronine (T3) and thyroxine (T4) in the blood of breast-fed babies.

(25) http://newscenter.berkeley.edu/2010/06/21/pbde/
Exposure to flame retardants linked to changes in thyroid hormones.
By Sarah Yang, Media Relations | June 21, 2010

(26) http://www.actabiomedica.it/data/2008/3_2008/costa.pdf
ACTA BIOMED 2008; 79: 172-183 Polybrominated diphenyl ether (PBDE) flame retardants: environmental contamination, human body burden and potential adverse health effects Lucio G. Costa1, 3, Gennaro Giordano3, Sara Tagliaferri1, Andrea Caglieri2, Antonio Mutti2

Hormonal Disruption by Pesticide exposure

(27) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1524969/?tool=pubmed
Reprod Biol Endocrinol. 2006; 4: 30.
Published online 2006 May 31. doi: 10.1186/1477-7827-4-30. PMCID: PMC1524969

Pesticide exposure: the hormonal function of the female reproductive system disrupted?
Reini W Bretveld,1 Chris MG Thomas,2 Paul TJ Scheepers,1 Gerhard A Zielhuis,1 and Nel Roeleveld1

(28) http://www.bioscienceresource.org/cms/documents/From%20silent%20spring%20to%20silent%20night.pdf
From silent spring to silent night: endocrine disruption, amphibian declines, and environmental justice

(29) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1533073/pdf/envhper00538-0037.pdf
Developmental Neurotoxicology of Endocrine Disruptors and Pesticides: Identification
of Information Gaps and Research Needs Hugh A. Tilson
National Health and Environmental Effects Research Laboratory,
U.S. Environmental Protection Agency, Research Triangle Park, North Carolina

(30) http://www.slovetres.si/files/pdf/volume2010/vol47_4/SlovVetRes_47_4_163-6.pdf
Slov Vet Res 2010; 47 (4): 163-6 UDC 502/504:615
PESTICIDES AS ENDOCRINE DISRUPTORS Katerina Čeh1*, Gregor Majdič1,2

(31) http://www.biomedcentral.com/content/pdf/1477-7827-4-30.pdf
Pesticide exposure: the hormonal function of the female reproductive system disrupted?
Reini W Bretveld1, Chris MG Thomas2, Paul TJ Scheepers1,
Gerhard A Zielhuis1 and Nel Roeleveld*

(31A) http://www.westonaprice.org/environmental-toxins/246-timeline-of-endocrine-disruption-and-man-made-chemicals.html
Timeline of Endocrine Disruption and Man-Made Chemicals Weston-Price

(31http://www.ourstolenfuture.org/
The book Our Stolen Future brought world-wide attention to scientific discoveries about endocrine disruption and the fact that common contaminants can interfere with the natural signals controlling development of the fetus. This website tracks the most recent developments.

(32) http://www.grinningplanet.com/2006/update-2005-05-24/pesticides-in-food.htm
BAD RESIDUALS FROM DAILY RERUNS OF “EATING YOUR FOOD”
Reduce Your Exposure to Pesticides in Food Through Smart Food Choices

Increasing Global Pesticide USE- 1% per year

(33) http://www.wri.org/publication/content/8660
World pesticide use. Organochlorine insecticides such as DDT, lindane, and toxaphene are still widely used in the developing world, although their danger to humans and animals is well known. Many developed countries have banned or severely restricted the most toxic of these compounds but continue to manufacture and sell them. Trade in restricted and banned pesticides is almost impossible to track, but customs records for shipments from the United States show that at least 108,000 metric tons of banned, restricted, or discontinued pesticides were exported from U.S. ports from 1992 to 1994

(33) http://www.farmingsolutions.org/facts/factscontent_det.asp?cnt=0&id=4
UK based consultants Allan Woodburn Associates predicts that the global agrochemical market will increase by 1% on average each year over the next five years to approximately US$31.4 billion in 2005. (Agrow: World Crop Protection News, March 2, 2000)

(35) http://www.flavorfood.com.br/artigos/perigos_quimicos/Contaminantes%20ambientais/Agriculture,%20pesticides,%20food%20security%20and%20food%20safety.pdf
Agriculture, pesticides, food security and food safety Fernando P. Carvalho * Instituto Tecnolo´ gico Portugal

The use of agrochemicals, including pesticides, remains a common practice especially in tropical regions and South countries. Cheap compounds, such as DDT, HCH and lindane, that are environmentally persistent, are today banned from agriculture use in developed countries, but remain popular in developing countries. As a consequence, persistent residues of these chemicals contaminate food and disperse in the environment.

The world population grew from 2.5 billion in 1950 to 6.1 billion in the year 2000. By the year 2050 the world population is estimated to reach 9.1 billion (between 7.7 and 10.6 billion, depending on estimates). This means that the population of Earth more than doubled in the past 50 years, from 1950 to 2000, and will probably grow only slightly less in the 50 years from 2000 to 2050 (Fig. 1).

Currently, world population is growing with an annual rate of 1.2%,
Pesticide use is also growing at a 1% per year rate.

Neurotoxicity

(36) http://www.reach-compliance.eu/english/documents/studies/neurotoxity/PGrandjean–PjLandrigan.pdf Developmental neurotoxicity of industrial chemicals P Grandjean, PJ Landrigan

(37) http://ehp03.niehs.nih.gov/article/fetchArticle.action?articleURI=info%3Adoi%2F10.1289%2Fehp.1002234

PON1 and Neurodevelopment in Children from the CHAMACOS Study Exposed to Organophosphate Pesticides in Utero

Brenda Eskenazi1, Karen Huen1, Amy Marks1, Kim G. Harley1, Asa Bradman1, Dana Boyd Barr2, Nina Holland1. 1 Center for Environmental Research and Children’s Health, School of Public Health, University of California, Berkeley, Berkeley, California, USA, 2 Emory University, Rollins School of Public Health, Atlanta, Georgia, USA

TESTING for environmental pollutants in Humans

(38) http://www.usbiotek.com/news_toxic_chemicals.php
US BioTek’s Environmental Pollutants Panel measures the phthalate metabolite, MEP in addition to metabolites of 6 other environmental toxicants. This panel is available from simple spot urine that utilizes our proprietary Dip ’N Dry urine collection strip to maximize analyte stability and recovery.

US BioTek Laboratories News

The Senate Meets to Examine Risks of Toxic Chemicals to Children’s Health
On October 26, 2010 the Subcommittee on Superfund, Toxics, and Environmental Health Field held a Hearing entitled, “Toxic Chemicals and Children’s Environmental Health.” Under the leadership of Senator Lautenberg of New Jersey, this hearing was scheduled to discuss the environmental health effects from children’s exposure to common chemicals in our environment and serve to initiate legislative reform of the Toxic Substances Control Act (TSCA) of 1976.

(39) http://www.usbiotek.com/Services_Environmental-Pollutants-Panel.php
US BioTek Laboratories’ Environmental Pollutants Profile quantifies exposure to select environmental toxins: aromatic solvents, paraben and phthalates.

http://www.slideshare.net/metametrix/environmental-toxicity-and-the-effect-on-health
Environmental Toxicity and the Effect on Health – Metametrix

Liver Detoxification

(40)http://www.liverdoctor.com/index.php?page=liver-detoxification
THE LIVER AND DETOXIFICATION
More than ever before in the history of mankind, human beings need to have healthy livers to break down the chemicals that have crept into our environment. If you talk to radiologists and gastroenterologists who are looking at people’s livers today they will tell you that the condition “Fatty Liver” affects more than 50% of people over the age of 50!

(41) http://www.renewlife.com/liver-detox.html
Natural 2-part Liver Detoxification & Body Cleansing Program

2-part liver detox formula promotes natural organ detoxification‡
Formulated with herbs and nutraceuticals used to support normal liver function‡

Liver Detox is an advanced and comprehensive liver support product.* Its proprietary formulation of 17 herbs and nutraceuticals is designed to simultaneously support, protect, stimulate and assist your body’s natural detoxification of the liver.* Liver Detox stimulates bile production and the existing detoxification mechanisms of the liver.* It also contains compounds that help protect the cells of the liver, and provides fuel that the liver needs to form important antioxidants, which neutralize toxins.* Liver Detox is a support product, and can be taken daily with all other ReNew Life cleansing products.*

•2-part liver detox formula promotes natural organ detoxification*
•Formulated with herbs and nutraceuticals used to support normal liver function*
•30-Day Program
•Gluten-Free
A properly functioning liver is vital to health.

What is the liver and how does it function? The liver is your largest internal organ and it performs many functions including detoxification of the body. The liver works by both filtering toxins directly and by altering toxins so that they can be removed at other stages of detoxification. The liver filters toxins from one quart of blood every minute. After the liver processes these endotoxins (produced in the body), exotoxins (from outside the body) and other wastes, they are sent to the kidneys and colon for elimination.

Liver Detox is an easy-to use, two-part cleansing and detoxification program formulated to simultaneously support, protect, stimulate and assist with the body’s natural detoxification of the liver with natural minerals, vitamins, herbs and amino acids.* Both the Morning Formula (Part I) and the Evening Formula (Part II) contain minerals, herbs and amino acids that may help promote healthy liver function.*

Liver Detox includes:

Milk Thistle – an herb used traditionally to support normal detoxification functions of the liver.* The antioxidant activity of the main ingredient in milk thistle (silymarin) may help promote healthy liver function and protect healthy liver cells.*

L-Methionine – amino acid that the liver uses to create glutathione. Glutathione is powerful amino acid made by the liver, which acts as an antioxidant and detoxifying compound.* Supplementing with L-methionine can help raise glutathione levels.

N-Acetyl-Cysteine (NAC) – the liver also uses NAC to create glutathione. Supplementing with NAC can help raise glutathione levels and thus support the natural detoxification functions of the liver.*

Alpha Lipoic Acid – antioxidant that helps revitalize glutathione and supports detoxification.*

Selenium – essential trace mineral that enhances the antioxidant power of zinc and vitamins to allow them to function better in their natural detoxification roles.*

Ayurvedic Herbs – used to promote the natural detoxification capabilities of the liver.* Among the most commonly used herbs are Boerhavia Diffusa, Eclipta Alba, Terminalia Belerica, Tinospora Cordifolia, and Picrorhiza Kurroa.

Dandelion – herb used traditionally to stimulate bile production and promote healthy liver detoxification.*
(42) http://www.detoxreviews.com/

Detox and Cleansing Product Reviews

(43) http://www.drnatura.com/cleanse-detox/
#1 Selling and “Voted” most Popular Colon Cleansing and Body Detox Resource in the World
Why Do You Need a Detox or Colon Cleanse Product?

(44) http://www.garmaonhealth.com/2009/08/detoxifying-your-way-to-nirvana/
Detoxifying Your Way to Nirvana
Written by Joe Garma

(45) www.dysbiosis.com

(46) http://curezone.com/upload/PDF/Books/Polly_Hattemer_Book_1_Candida.pdf
Candida’s Impact on Your Health Edited and Compiled by Polly Hattemer Foreword by Sondra K. Lewis

(47) http://www.gilbertssyndrome.com/detoxification.php
The Detoxification System

nice article

(48) http://www.hchs.edu/literature/Detoxification.pdf
Detoxification Dietary Supplements to Support & Promote the Process By Gene Bruno, MS, MHS

(49) http://www.purecaps.com/PDF/pi/Liver_GI%20Detox.pdf
Liver-G.I. Detox pure encapsulations product combo

(50) http://www.adltests.com/assets/files/pdf/Liver_Detoxification_Review_Liska.pdf

The Detoxification Enzyme Systems by DeAnn J. Liska, Ph.D.

Abstract
The human body is exposed to a wide array of xenobiotics in one’s lifetime, from
food components to environmental toxins to pharmaceuticals, and has developed
complex enzymatic mechanisms to detoxify these substances. These mechanisms
exhibit significant individual variability, and are affected by environment, lifestyle, and
genetic influences. The scientific literature suggests an association between impaired
detoxification and certain diseases, including cancer, Parkinson’s disease, fibromyalgia,
and chronic fatigue/immune dysfunction syndrome. Data regarding these hepatic
detoxification enzyme systems and the body’s mechanisms of regulating them suggests
the ability to efficiently detoxify and remove xenobiotics can affect these and other
chronic disease processes. This article reviews the myriad detoxification enzyme
systems; their regulatory mechanisms; and the dietary, lifestyle, and genetic factors
influencing their activities; as well as laboratory tests available to assess their functioning.
(Altern Med Rev 1998;3(3):187-198)

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http://deepblue.lib.umich.edu/bitstream/2027.42/21795/1/0000194.pdf
Ascorbic acid and drug detoxification V.G. Zannoni and L. E. Rikans
Ascorbic acid plays apart in maintaining adequate drug detoxification and its biochemical
mode of action is of current interest.

Fetal livers with an ascorbic acid concentration of below 5.0 mg/100 g liver had no detectable
cytochrome P-450 or O-demethylase activity while livers with high ascorbic acid
levels (above 17.0 mg/100 g liver) had much higher drug metabolism activity;

http://www.drlepine.com/drtl/bm~doc/detoxification-explained.pdf

TECHNICAL BULLETIN D E T O X I F I C A T I O N BIOCHEMISTRY

http://www.ohiond.com/articles/Environmental%20Toxicity.pdf
Protecting Your Family from Environmental Toxicity By: Dr. Ted Suzelis, N.D.

http://www.sfms.org/AM/Template.cfm?Section=Home&template=/CM/HTMLDisplay.cfm&ContentID=1643
Changing Patterns of Disease: Human Health and the Environment Ted Schettler, MD, MPH

http://www.healthandenvironment.org/birth_defects/peer_reviewed
Birth Defects and the Environment Betty Mekdeci, Birth Defect Research for Children
Ted Schettler, MD, MPH, Science and Environmental Health Network
May 2004

http://www.healthandenvironment.org/science/peer_reviewed
Peer Reviewed Papers

Metal detox

http://www.radianthealthnow.net/nutritionarticle67.html
PROTECTING YOURSELF FROM ENVIRONMENTAL TOXICITY: 5 WAYS TO DETOXIFY CHEMICALS & HEAVY METALS By: Michael McEvoy, CNC, CMTA 11-1-10

http://www.mercout.com/pages.php?pageid=42
The “Provoked Urine Challenge”: The Most Accurate Way to Test Your Mercury Level

Mark Hyman MD

http://www.huffingtonpost.com/dr-mark-hyman/is-there-toxic-waste-in-y_b_460720.html
Is There Toxic Waste in Your Body? Posted on July 21st, 2009 Mark Hyman, M.D.

http://www.ultrawellness.com/blog/ultrawellness-key-5
http://drhyman.com/is-there-toxic-waste-in-your-body-494/
Is There Toxic Waste in Your Body? Posted by Mark Hyman MD July 21st, 2009

http://drhyman.com/how-to-rid-your-body-of-mercury-and-other-heavy-metals-a-3-step-plan-to-recover-your-health-523/
How to Rid Your Body of Heavy Metals: A 3-Step Detoxification Plan. Mark Hyman md

http://www.noamalgam.com/
Amalgam Illness Diagnosis and Treatment A book on how to cure mercury poisoning
by Andrew Hall Cutler, PhD, PE

http://amalgamillness.com/index.html
In July of 2000, the owners of Herb Allure, Inc. had all their amalgam (a.k.a. “Silver” [mercury-containing]) dental fillings replaced and their lives changed dramatically. Since then, we’ve been passionately sharing the unbelievable information our research uncovered that caused us to make this life-changing decision.
We personally believe chronic mercury poisoning from amalgam (“silver”) fillings is the most important health subject of the next decade. Many or most of the people you know probably already have it, don’t know it, and are treating other symptoms which are rooted in one of mercury’s many dangerous side effects.

http://www.autismpedia.org/wiki/images/b/b9/Andy_protocol.PDF
ALA/DMSA Mercury Detoxification Protocol by Andrew Hall Cutler,

Politics of Chemical Pollution

http://www.psr.org/news-events/press-releases/toxic-chemicals-found-in-doctors-and-nurses.html

http://www.psr.org/assets/pdfs/hazardous-chemicals-in-health-care.pdf
A Snapshot of Chemicals in Doctors and Nurses

Physicians for Social Responsibility (PSR) in partnership with American Nurses Association (ANA) and Health Care Without Harm (HCWH) have released the “Hazardous Chemicals In Health Care” report, detailing the first investigation ever of chemicals found in the bodies of health care professionals. The inquiry found that all of the 20 participants had toxic chemicals associated with health care in their bodies. Each participant had at least 24 individual chemicals present, four of which are on the recently released Environmental Protection Agency list of priority chemicals for regulation. These chemicals are all associated with chronic illness and physical disorders.

http://healthychild.org/blog/comments/30_states_will_announce_bills_to_protect_kids_from_toxic_chemicals/
30 States Will Announce Bills to Protect Kids from Toxic Chemicals Healthy Child Tuesday, January 18, 2011

http://iatp.typepad.com/healthy_legacy/2011/01/we-wont-take-it-anymore-minnesota-and-29-other-states-want-toxics-out-of-our-productsand-our-lives.html
Minnesota, 29 Other States and DC Announce Legislation to Get Toxics Out of Products

http://www.thecanaryreport.org/2010/10/16/toxic/
Sad news for canaries: toxic chemical reform bills are dead Oct 16, 2010 by Susie Collins in Blog, Law, Susie Collins One year ago, the outlook for reform of the toxic substances act was good. But then, in the first six months of 2010, the chemical industry spent more than $40 million on lobbying. And now the toxic chemical reform bills are dead.

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